Do statins and hormonal replacement therapy in combination reduce cardiovascular risk in postmenopausal women?
نویسنده
چکیده
[1] Elizari MV, Martı́nez JM, Belziti C et al. Morbidity and mortality following early administration of amiodarone in acute myocardial infarction. Eur Heart J 2000; 21: 198–205. [2] Burkart F, Pfisterer M, Kiowski W, Follath F, Burckhardt D. Effect of antiarrhythmic therapy on mortality in survivors of myocardial infarction with asymptomatic complex ventricular arrhythmias: Basel Antiarrhythmic Study of Infarction Survival (BASIS). J Am Coll Cardiol 1990; 16: 1711–18. [3] Ceremuzynski L, Kleczar E, Kreminska-Pakula M et al. Effect of amiodarone on mortality after myocardial infarction: a double blind, placebo-controlled pilot study. J Am Coll Cardiol 1992; 20: 1051–62. [4] Julian DG, Camm AJ, Frangin G, Janse MJ, Munoz A, Schwartz PJ, Simon P. Randomised trial of effect of amiodarone on mortality in patients with left-ventricular dysfunction after recent myocardial infarction: EMIAT. Lancet 1997; 349: 667–74. [5] Cairns JA, Connolly SJ, Roberts R, Gent M. Randomised trial of outcome after myocardial infarction in patients with frequent or repetitive ventricular premature depolarisations: CAMIAT. Lancet 1997; 349: 675–82. [6] Scheinman , MM, Levine JH, Cannom DS et al. Dose ranging study of intravenous amiodarone in patients with life threatening ventricular arrhythmias. Circulation 1995; 92: 3264–72. [7] Gomes JA, Winters SL, Ip J. Signal averaging of the surface QRS complex: practical applications. J Cardiovasc Electrophysiol 1991; 2: 316–30. [8] Kleiger RE, Miller JT, Moss AJ. Decreased heart rate variability and its association with increased mortality after acute myocardial infarction. Am J Cardiol 1987; 59: 256–62. [9] Bigger JT Jr, LaRovere MT, Steinman RC et al. Comparison of baroreflex sensitivity and heart period variability after myocardial infarction. J Am Coll Cardiol 1989; 14: 1511–18. [10] Malik M, Camm AJ, Julian DG et al. EMIAT Investigators. Amiodarone reduces mortality in patients with first myocardial infarction and reduced heart rate variability retrospective substudy of the EMIAT Trial (Abstr). PACE 1997; 20: 1090. [11] Hohnloser SH, Klingenheben T, Li YG, Zabel M, Peetermans J, Cohen RJ. T wave alternans as a predictor of recurrent ventricular tachyarrhythmias in ICD recipients: prospective comparison with conventional risk markers. J Cardiovasc Electrophysiol 1998; 9(12): 1258–68.
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ورودعنوان ژورنال:
- European heart journal
دوره 21 3 شماره
صفحات -
تاریخ انتشار 2000